Severe Hypertriglyceridaemia Following Initiation of Mirtazapine

Management of severe hypertriglyceridaemia.

Diagnostic approach to and management of SHTG are not always straightforward and specialist knowledge is required, particularly with the expected increase in the rates of SHTG associated with obesity and diabetes epidemics. We hope that this article will prove helpful for physicians caring for such patients. Their management may be guided by our recommendations that are shown in Table 2.

Severe hypertriglyceridaemia responding to insulin and nicotinic acid therapy.

A patient with unusually severe hypertriglyceridaemia (serum concentration initially 258 mmol/l or 22600 mg/dl) and hypercholesterolaemia is reported and discussed. The triglyceride elevation was found to reside within the very low density lipoprotein fraction and was probably attributable to the combination of diabetes mellitus and familial hypertriglyceridaemia. Treatment with insulin and res...

Artifactually low glycated haemoglobin in a patient with severe hypertriglyceridaemia.

This report describes a case of artifactually low glycated haemoglobin (Hb) in a patient with type II diabetes and severe hypertriglyceridaemia. The effect of hypertriglyceridaemia on glycated Hb determination using the Abbott Vision method was investigated in a series of patients with diabetes. The interference of triglycerides in glycated Hb assays was also investigated by two other methods, ...

Severe hypertriglyceridaemia as a result of familial chylomicronaemia: the Cape Town experience.

Lipoprotein lipase deficiency causes severe hypertriglyceridaemia due to chylomicronaemia, and leads to recurrent and potentially life-threatening pancreatitis. This disorder can only be managed by dietary fat restriction as drugs are ineffective. We review the experience with familial chylomicronaemia in patients who attended the lipid clinics at Groote Schuur Hospital and Red Cross Children's...

Unmasking of severe hypertriglyceridaemia associated with antipsychotic therapy by atypical eruptive xanthomas